Definitely not going to hot spots for fighting will keep you out of fights.

Other ways to stay out of fights is to not be a drunken ass hole, not be an over emotional poser, not be an ignorant dick to someone else's mate etc etc.

Besides that, there are plenty of ways to restrain someone from striking you and to also allay any chance of them seriously injuring themselves.

If you are in your 20's, like to club, are looking for love or sex quite often, then chances are, you might wind up in a fight. C'est La Vie.